SIBO & Ginger

SIBO & Ginger

Small intestine motility dysfunction is an issue in small intestine bacterial overgrowth (SIBO). Agents that promote stomach emptying can also be helpful in treating and preventing relapse of SIBO. Ginger modulates serotonin signaling by 5-HTP4 stimulation. This is also the mechanism of action of the pro kinetic agent Resolor (Proclapride) used in preventing SIBO. Resolor promotes multiple MMC waves vs. low dose erythromycin which stimulates one MMC wave. Gingerols have been found to promote gastroduodenal emptying rate and motility in (24) healthy volunteers and the effect of a ginger rhizome extract (2 x 100 mg) was studied on fasting and postprandial gastroduodenal motility with stationary manometry.

 

SIBO, Autotimmunity & Food Coloring

SIBO, Autotimmunity & Food Coloring

Artificial colors are small molecule chemicals and the proper way to measure antibodies to such chemicals is by testing the chemical bound to human tissue. These chemicals and/or their metabolites can trigger inflammatory cytokines. This results in proteins that accumulate in the gastrointestinal tract and cause inflammation. This inflammation can then lead to the opening of the tight junctions and may then lead to intestinal permeability and trigger autoimmunity or relapse in SIBO.

SIBO Diet, Autoimmunity & Gums

SIBO Diet, Autoimmunity & Gums

Low FODMAP eating plan while either treating or maintaining your SIBO results often contain gums. Gums are most often used as replacement for wheat gluten and are in many gluten free products. They are also found in many processed foods in the form of emulsifiers, stabilizers, thickeners, food additives, glazing agents and even in fire retardant gelling agents and often act as endocrine disrupting chemicals (EDCs).